黑台子曝光论坛

临床前研究

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代谢性疾病

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生长发育

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辅助生殖

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肿瘤

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Gensci 047 是抗PD-L1全人源单克隆抗体,可用于多种肿瘤的治疗。
以PD-1/PD-L1 等免疫检查点抑制剂为代表的免疫疗法,在全球多个公司开展的临床试验中,取得了突破性的、确切的抗肿瘤治疗效果,代表了目前全球肿瘤治疗的方向。目前,全球已有罗氏、阿斯利康、BMS等五个PD-1/PD-L1新药获批上市,涉及黑色素瘤、非小细胞肺癌等10余种适应症。
Gensci 059 继PD-1/PD-L1之后的新一代免疫检查点抑制剂,可用于多种肿瘤的治疗。 待补充 BA002、BA003,也是双功能抗体,作为一个新型的分子,是目前在国内国际上发展的一个大的趋势和进一步研发的新方向。我公司研究具有良好的稳定双功能分子结构,避开其他公司已有的专利,做出一个新的分子结构,从而保证我们分子在结构上的先进性。 BT001是双功能Trap,作为一个新型的分子,也是目前在国内国际上发展的一个大的趋势和进一步研发的新方向。我公司研究具有良好的稳定双功能分子结构,避开其他公司已有的专利,做出一个新的分子结构,从而保证我们分子在结构上的先进性。

炎症自身免疫疾病

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Gensci 048是全人源单克隆抗体,主要用于炎症自身免疫性疾病。是重要的促炎症细胞因子,它介导的的炎症反应是多种自身免疫性疾病和心血管疾病发病的关键因素。目前国内没有上市产品,我公司研制成功将对广大患者带来福音。 Gensci 069是抗IgE人源化单克隆抗体,Xoliar(Omalizumab)的生物类似药,用于治疗中重度过敏性哮喘。 Omalizumab是Genentech公司用于哮喘治疗的疗效确切,但至今尚未进入中国市场。国内患者无法从正规途径购买,而且国际市场上价格较高。 X001、X002、X003是人源化抗体,用于自身免疫性疾病中的系统性红斑狼疮、过敏性哮喘、银屑病等疾病的治疗。

中枢神经系统疾病

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Gensci 063是新型治疗阿尔茨海默症(老年痴呆症)的单克隆抗体药物。 Gensci 066是新型治疗阿尔茨海默症(老年痴呆症)的单克隆抗体药物。
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